Description

Butanoic Acid, 2-Fluoro-2-Methyl-3-Oxo-, Ethyl Ester is a specialized fluorinated ketoester building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. Industries requiring high-purity, custom synthetic intermediates for research and development, including medicinal chemistry and fine chemical manufacturing, are the primary users of this material.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing fluorinated motifs to enhance potency and pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can improve efficacy and environmental stability.
• Fine Chemical Production: Acts as a versatile precursor for the manufacture of complex fluorinated esters, acids, and other derivatives used in specialty chemicals.
• Material Science Research: Employed in the development of novel fluorinated polymers or coatings with unique surface properties and chemical resistance.
• Medicinal Chemistry & Drug Discovery: A valuable scaffold for constructing diverse compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Butanoic Acid, 2-Fluoro-2-Methyl-3-Oxo-, Ethyl Ester
CAS No.	122795-13-5
Molecular Formula	C7H11FO3
Molecular Weight	162.16 g/mol
Synonyms	Ethyl 2-Fluoro-2-methyl-3-oxobutanoate; 2-Fluoro-2-methyl-3-oxo-butanoic acid ethyl ester; 3-Oxobutanoic acid, 2-fluoro-2-methyl-, ethyl ester; Ethyl 2-fluoroacetoacetate derivative; Fluoromethyl ethyl acetoacetate; 2-Fluoro-2-methylacetoacetic acid ethyl ester; Ethyl 2-fluoro-2-methyl-3-oxobutyrate
EINECS	Contact for details

Quality Control

Our Butanoic Acid, 2-Fluoro-2-Methyl-3-Oxo-, Ethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 8°C for extended stability, although short-term storage at controlled room temperature (15-25°C) is acceptable. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Specific Gravity (20°C)	1.10 - 1.20

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.