Description

Neurotoxin Iii, Radianthus Macrodactylus is a potent polypeptide neurotoxin isolated from the sea anemone species *Radianthus macrodactylus*. This compound is of significant interest for its specific activity on voltage-gated sodium channels, making it a valuable tool for neurological and pharmacological research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuroscience, ion channel studies, and drug discovery.

Application

• Neuroscience Research: As a selective probe for studying the structure and function of voltage-gated sodium channels in neuronal cells.
• Pharmacological Studies: Used in the development and screening of novel analgesic or neuroprotective drug candidates targeting sodium channels.
• Ion Channel Characterization: A critical reagent for electrophysiology assays (e.g., patch-clamp) to investigate channel gating and kinetics.
• Toxicology & Venom Research: Serves as a reference standard in the study of marine toxins and their mechanisms of action.
• Biochemical Reagent: Employed in the purification and isolation of specific sodium channel subtypes from tissue preparations.
• Academic & Industrial R&D: Fundamental research tool in university labs and biotech firms for basic science and applied therapeutic discovery.

Basic Information

Product Name	Neurotoxin Iii, Radianthus Macrodactylus
CAS No.	122781-94-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	RTX-III; Radianthus macrodactylus toxin III; Sea Anemone Neurotoxin III; Sodium Channel Neurotoxin RTX-III; *Radianthus macrodactylus* polypeptide toxin; Neurotoxin III (R. macrodactylus); Anemone Neurotoxin III
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Neurotoxin III is characterized using advanced analytical techniques to confirm identity, purity, and biological activity. Certificates of Analysis (COA) detailing purity (by HPLC), molecular weight confirmation, and bioactivity data are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere or desiccated conditions. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity	Confirmed by assay
Water Content (KF)	≤ 5.0%
Endotoxin Level	< 1.0 EU/µg (where applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.