Description

tert-Butyl (S)-1-(n-Methoxy-n-Methylcarbamoyl)-2-Hydroxyethylcarbamate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering precise stereochemical control for the development of active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in the development of novel therapeutics and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of protease inhibitors and other biologically active compounds.
• Peptidomimetic Research: Used in the construction of peptide analogs and mimetics for drug discovery programs targeting various diseases.
• Asymmetric Synthesis: Serves as a protected amino acid derivative for introducing the (S)-2-amino-1-hydroxyethyl moiety in stereoselective reactions.
• API Development: Employed in the research and scale-up production of candidate drug molecules, particularly in oncology and antiviral fields.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Chemical Biology: Utilized as a tool compound or precursor in the study of enzyme mechanisms and biochemical pathways.

Basic Information

Product Name	tert-Butyl (S)-1-(n-Methoxy-n-Methylcarbamoyl)-2-Hydroxyethylcarbamate
CAS No.	122709-20-0
Molecular Formula	C11H22N2O5
Molecular Weight	262.31 g/mol
Synonyms	(S)-tert-Butyl 1-((Methoxy(methyl)amino)-1-oxo-3-hydroxypropan-2-yl)carbamate; (S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxy-N-methoxy-N-methylpropanamide; Boc-L-Serine-N-methoxy-N-methylamide; Boc-Ser-N(OMe)Me; N-Boc-L-serine N-methyl-N-methoxy amide; N-(tert-Butoxycarbonyl)-L-serine N-methoxy-N-methylamide; tert-Butyl (S)-(1-(methoxy(methyl)amino)-1-oxo-3-hydroxypropan-2-yl)carbamate; 122709-20-0
EINECS	Contact for details

Quality Control

Our tert-Butyl (S)-1-(n-Methoxy-n-Methylcarbamoyl)-2-Hydroxyethylcarbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.