Description

Bis(3,5-Dimethyl-4-Methoxyphenyl)Phosphine is a specialized organophosphorus compound featuring sterically hindered, electron-rich methoxy-substituted aryl groups. This structure makes it a valuable ligand in transition metal catalysis, particularly for coupling reactions requiring high activity and selectivity. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel synthetic pathways and optimizing production processes.

Application

• As a ligand in cross-coupling catalysis (e.g., Suzuki-Miyaura, Heck, Buchwald-Hartwig reactions).
• In the synthesis of pharmaceutical intermediates and active ingredients requiring precise stereochemical control.
• For the development of specialty polymers and advanced materials with tailored electronic properties.
• In agrochemical research for creating novel active compounds.
• As a precursor or modifying agent in organometallic chemistry and material science.
• For academic and industrial R&D in exploring new catalytic systems.

Basic Information

Product Name	Bis(3,5-Dimethyl-4-Methoxyphenyl)Phosphine
CAS No.	122708-97-8
Molecular Formula	C18H23O2P
Molecular Weight	302.35 g/mol
Synonyms	Bis(4-Methoxy-3,5-dimethylphenyl)phosphine; (3,5-Dimethyl-4-methoxyphenyl)phosphine (dimer); Phosphinidene, bis(3,5-dimethyl-4-methoxyphenyl)-; Ligand for cross-coupling; Sterically hindered phosphine ligand
EINECS	Contact for details

Quality Control

Our Bis(3,5-Dimethyl-4-Methoxyphenyl)Phosphine is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency. Quality is verified through comprehensive analytical techniques including NMR, HPLC, and elemental analysis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). Due to its sensitivity to oxidation, containers should be purged with inert gas after each opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.