Description

3-Aminocarbonyl-1-Boc-Pyrrolidine is a high-purity, protected pyrrolidine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing a Boc-protected amine and a carboxamide functional group, enabling precise molecular construction. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in medicinal chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug molecules, especially protease inhibitors and other nitrogen-containing heterocycles.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes and tool compounds to study biological pathways.
• Agrochemical Synthesis: Employed in the research and development of advanced crop protection agents and pesticides.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and catalysis studies.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	3-Aminocarbonyl-1-Boc-Pyrrolidine
CAS No.	122684-34-8
Molecular Formula	C10H18N2O3
Molecular Weight	214.26 g/mol
Synonyms	1-Boc-3-carbamoylpyrrolidine; 1-(tert-Butoxycarbonyl)-3-pyrrolidinecarboxamide; 3-Carbamoyl-1-Boc-pyrrolidine; tert-Butyl 3-carbamoylpyrrolidine-1-carboxylate; 1-Boc-pyrrolidine-3-carboxamide; Pyrrolidine-3-carboxamide, 1-[(1,1-dimethylethoxy)carbonyl]-; 1-N-Boc-3-aminocarbonylpyrrolidine; Boc-3-CAM-pyrrolidine
EINECS	Contact for details

Quality Control

Our 3-Aminocarbonyl-1-Boc-Pyrrolidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to maintain product integrity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.