Description

Cdc6 Protein CAS NO 122544-18-7 is a critical regulatory protein essential for the initiation of DNA replication in eukaryotic cells. This high-purity recombinant protein is vital for researchers studying cell cycle control, DNA replication licensing, and the mechanisms underlying genomic stability. It is an indispensable reagent for molecular biology, biochemistry, and oncology research, enabling detailed in vitro studies of replication origin assembly and checkpoint signaling. Leading pharmaceutical and biotechnology R&D laboratories rely on it for target validation and screening in drug discovery programs focused on cancer therapeutics.

Application

• Cell Cycle and DNA Replication Research: Fundamental studies on the initiation and regulation of DNA synthesis.
• Biochemical Assay Development: Used as a key component in enzymatic assays to study pre-replication complex (pre-RC) formation.
• Cancer Biology Studies: Investigation of dysregulated replication in oncogenesis and tumor progression.
• Drug Discovery & Target Validation: Screening platform for identifying inhibitors that target the replication licensing machinery.
• Protein-Protein Interaction Studies: Tool for mapping interactions with other replication factors like ORC, Cdt1, and MCM helicases.
• Educational & Diagnostic Kit Manufacturing: Component in advanced research kits for academic and clinical laboratories.

Basic Information

Product Name	Cdc6 Protein
CAS No.	122544-18-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cell Division Cycle 6 Protein; CDC6; CDC6 Homolog; Replication Licensing Factor CDC6; HsCDC6; p62CDC6; DNA Replication Licensing Factor MGC126616
EINECS	Contact for details

Quality Control

Our Cdc6 Protein is produced under stringent conditions to ensure the highest levels of purity and biological activity. Each lot undergoes comprehensive analytical testing, including SDS-PAGE, Western Blot, and functional activity assays, to guarantee consistency and performance. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, concentration, and specific activity. We adhere to rigorous quality management principles to support reproducible research outcomes.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C to -80°C. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Identification (SDS-PAGE/Western Blot)	Complies
Purity (SDS-PAGE)	> 95%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Functional Assay)	Confirmed
Protein Concentration	Specified on COA
Buffer Composition	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.