Description

tert-Butyl {(S)-1-Methyl-2-Oxo-2-[(S)-Pyrrolidin-3-Ylamino]Ethyl}Carbamate is a high-purity, chiral organic intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters because it serves as a critical building block for constructing complex molecules with specific stereochemistry, enabling the development of targeted therapeutics. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in areas like protease inhibitors and other specialized drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Serves as a crucial precursor in the development of novel protease inhibitors for therapeutic applications.
• Peptidomimetic Chemistry: Used in the design and synthesis of peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce specific chiral centers into target molecules.
• Medicinal Chemistry R&D: A valuable tool for medicinal chemists in structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects on behalf of pharmaceutical clients.

Basic Information

Product Name	tert-Butyl {(S)-1-Methyl-2-Oxo-2-[(S)-Pyrrolidin-3-Ylamino]Ethyl}Carbamate
CAS No.	122536-66-7
Molecular Formula	C13H25N3O3
Molecular Weight	271.36 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)-N-((S)-pyrrolidin-3-yl)propanamide; Boc-L-Ala-NH-(S)-3-aminopyrrolidine; tert-Butyl (S)-1-((S)-3-aminopyrrolidine-1-carbonyl)ethylcarbamate; (S)-2-(tert-Butoxycarbonylamino)-N-((S)-pyrrolidin-3-yl)propionamide; (S)-N-((S)-3-Aminopyrrolidin-1-yl)-2-((tert-butoxycarbonyl)amino)propanamide; Boc-Ala-3-Apyr; 122536-66-7; Chiral Boc-protected amino acid pyrrolidine amide
EINECS	Contact for details

Quality Control

Our tert-Butyl {(S)-1-Methyl-2-Oxo-2-[(S)-Pyrrolidin-3-Ylamino]Ethyl}Carbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including chiral HPLC to confirm enantiomeric purity and identity verification. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request for every batch shipped.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.