Description

2-Amino-8-Methyl-3-(Trideuteromethyl)Imidazo[4,5-F]Quinoxaline CAS NO 122457-31-2 is a deuterated derivative of a heterocyclic aromatic amine, specifically designed for advanced research and analytical applications. This compound is of significant value as a stable isotope-labeled internal standard or tracer in mass spectrometry-based studies, enabling precise quantification and metabolic pathway analysis. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on toxicology, metabolism, and biomarker discovery.

Application

• Used as a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of its non-deuterated analog in complex matrices.
• Critical for metabolic and pharmacokinetic studies in pharmaceutical development, allowing researchers to track the fate of drug candidates and their metabolites.
• Employed in food safety and environmental analysis as a reference standard for detecting heterocyclic aromatic amines (HAAs), which are potential carcinogens formed during high-temperature cooking of protein-rich foods.
• Facilitates biomarker research and toxicological investigations by serving as a precise tracer to understand exposure levels and biological effects.
• Supports analytical method development and validation in regulatory and quality control laboratories, ensuring method accuracy and reproducibility.
• Essential in academic research exploring the formation mechanisms, chemical properties, and biological activities of imidazoquinoxaline derivatives.

Basic Information

Product Name	2-Amino-8-Methyl-3-(Trideuteromethyl)Imidazo[4,5-F]Quinoxaline
CAS No.	122457-31-2
Molecular Formula	C12H10D3N5
Molecular Weight	216.27 g/mol
Synonyms	2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline-d3; 8-Methyl-IQx-d3; MeIQx-d3; 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (trideuteromethyl-); 2-Amino-3-(trideuteromethyl)-8-methylimidazo[4,5-f]quinoxaline; Deuterated MeIQx; 3-(Trideuteromethyl)-2-amino-8-methylimidazo[4,5-f]quinoxaline; Isotope Labeled HAA Standard
EINECS	Contact for details

Quality Control

Our deuterated standards are produced under strict quality control protocols to ensure high isotopic purity and chemical integrity, critical for accurate analytical results. Each batch is characterized using advanced techniques including NMR, HPLC, and High-Resolution Mass Spectrometry (HRMS). Certificates of Analysis (COA) are provided, detailing the isotopic enrichment (typically >98 atom % D), chemical purity (by HPLC), and confirming the identity and structure of the compound.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. For long-term storage, consider storing desiccated at -20°C. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.