Description

(S)-Benzyl 2-((S)-2-(((Benzyloxy)Carbonyl)Amino)-5-Ureidopentanamido)-4-Methylpentanoate is a high-purity, protected peptide derivative designed for advanced pharmaceutical research and synthesis. This compound serves as a critical building block in the development of novel therapeutic agents, particularly in the field of protease inhibitors and other bioactive peptides. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for complex synthetic pathways. The product is supplied with full analytical documentation to ensure batch-to-batch consistency and support regulatory submissions.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), especially protease inhibitors.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS) for constructing complex peptide sequences.
• Bioconjugation: Used in the development of peptide-drug conjugates (PDCs) and other targeted therapeutic modalities.
• Chemical Biology Research: A valuable tool compound for studying enzyme-substrate interactions, signal transduction pathways, and protein function.
• Process Development: Employed in scaling up synthetic routes for candidate drugs during preclinical and clinical development stages.
• Reference Standard: Suitable for use as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(S)-Benzyl 2-((S)-2-(((Benzyloxy)Carbonyl)Amino)-5-Ureidopentanamido)-4-Methylpentanoate
CAS No.	122411-98-7
Molecular Formula	C27H36N4O6
Molecular Weight	512.60 g/mol
Synonyms	Z-L-Lys(Nε-Urea)-L-Leu-OBzl; Nα-Cbz-Nε-Urea-L-Lysyl-L-Leucine Benzyl Ester; Benzyl Nα-[(benzyloxy)carbonyl]-Nω-ureido-L-norleucyl-L-leucinate; Cbz-Lys(Urea)-Leu-OBzl; (S)-Benzyl 2-((S)-2-((((Benzyloxy)carbonyl)amino)-5-ureidopentanamido)-4-methylpentanoate; Z-L-Lys(Nε-urea)-L-Leu-OBzl; Nα-Carbobenzoxy-Nε-ureido-L-lysyl-L-leucine benzyl ester
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 2-((S)-2-(((Benzyloxy)Carbonyl)Amino)-5-Ureidopentanamido)-4-Methylpentanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.