Description

β-Epoetin CAS NO 122312-54-3 is a recombinant human erythropoietin (EPO) protein, a critical glycoprotein hormone that regulates red blood cell production. This high-purity biological is essential for therapeutic applications where stimulating erythropoiesis is required. It is primarily needed by the biopharmaceutical industry for the development and manufacturing of treatments for anemia associated with chronic kidney disease, chemotherapy, and other clinical conditions.

Application

• Pharmaceutical Active Ingredient: Core component in injectable formulations for treating anemia.
• Chronic Kidney Disease (CKD) Therapy: Used in medications to manage anemia in patients with renal failure.
• Oncology Supportive Care: Mitigates chemotherapy-induced anemia in cancer patients.
• Research & Development: Vital reference standard and reagent in hematology and cell biology research.
• Biosimilar Development: Serves as a key material for the development and characterization of biosimilar erythropoietin products.

Basic Information

Product Name	β-Epoetin
CAS No.	122312-54-3
Molecular Formula	C~809~H~1301~N~229~O~240~S~5~
Molecular Weight	~30,400 Da (glycosylated)
Synonyms	Epoetin Beta; Recombinant Human Erythropoietin Beta; rHuEPO-beta; Erythropoietin; EPO; Hemopoietin; Hematopoietin; CAS 122312-54-3
EINECS	Contact for details

Quality Control

Our β-Epoetin is manufactured under strict quality systems. Each batch is subjected to a comprehensive battery of analytical tests including identity, purity, potency, and impurity profiling to ensure it meets stringent pharmaceutical-grade specifications. Certificates of Analysis (COA) detailing results for assays such as SDS-PAGE, HPLC, and bioactivity are provided to guarantee compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be used immediately or stored as directed and must not be frozen. This product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (HPLC/Peptide Map)	Conforms to reference standard
Purity (SDS-PAGE, RP-HPLC)	≥ 98.0%
Potency (In vivo bioassay)	1.0 x 10^5 to 2.0 x 10^5 IU/mg
Protein Content (UV)	≥ 95.0% of stated mass
Endotoxin	< 1.0 EU/mg
Residual Host Cell DNA	< 10 pg/mg
Residual Host Cell Protein	< 100 ppm
Moisture (KF)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.