Description

2-(4-Fluoro-Benzyl)-3-Oxo-Butyric Acid Methyl Ester is a high-purity fluorinated organic building block essential for advanced chemical synthesis. This compound matters as a versatile intermediate, enabling the precise introduction of a fluorobenzyl moiety and a reactive β-keto ester functionality into target molecules. Pharmaceutical, agrochemical, and advanced material researchers need it for developing novel active ingredients and functional materials, leveraging its unique structural features for property optimization.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), including potential kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides where the fluorine atom enhances bioavailability and environmental stability.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic components.
• Chemical Research & Development: Serves as a versatile scaffold for heterocyclic chemistry, enabling the construction of complex molecular libraries for screening.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific fluorinated target molecules under cGMP or research-grade conditions.

Basic Information

Item	Detail
Product Name	2-(4-Fluoro-Benzyl)-3-Oxo-Butyric Acid Methyl Ester
CAS No.	122255-02-1
Molecular Formula	C12H13FO3
Molecular Weight	224.23 g/mol
Synonyms	Methyl 2-(4-Fluorobenzyl)-3-oxobutanoate; 3-Oxo-2-[(4-fluorophenyl)methyl]butanoic Acid Methyl Ester; 2-(4-Fluorobenzyl)acetoacetic Acid Methyl Ester; Methyl 2-(p-Fluorobenzyl)acetoacetate; 2-(4-Fluorobenzyl)-3-oxobutyric Acid Methyl Ester; Acetoacetic acid, 2-(p-fluorobenzyl)-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Fluoro-Benzyl)-3-Oxo-Butyric Acid Methyl Ester is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, providing full traceability and documentation. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request, supporting your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed when not in use to prevent moisture absorption and maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.