Description

tert-Butyl 2-Iodoethylcarbamate CAS NO 122234-46-2 is a versatile and high-purity organic building block featuring a protected amine group and a reactive iodoethyl moiety. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development, where it serves as a key intermediate for introducing functionalized ethylamine chains. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing ethylamine pharmacophores.
• Peptide Mimetics & Linker Chemistry: Used to introduce protected amine handles and alkyl spacers in peptide analogs and bioconjugation linkers.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the preparation of functionalized monomers for specialty polymers and advanced organic frameworks.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies and combinatorial library synthesis for drug discovery programs.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	tert-Butyl 2-Iodoethylcarbamate
CAS No.	122234-46-2
Molecular Formula	C7H14INO2
Molecular Weight	271.10 g/mol
Synonyms	Boc-2-Iodoethylamine; N-(tert-Butoxycarbonyl)-2-iodoethylamine; 2-Iodoethylcarbamic Acid tert-Butyl Ester; tert-Butyl N-(2-Iodoethyl)carbamate; N-Boc-2-iodoethylamine; (2-Iodoethyl)carbamic Acid 1,1-Dimethylethyl Ester; 1-Boc-2-iodoethylamine; BOC-NH-CH2-CH2-I
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Iodoethylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture uptake and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.