Description

3-(3-Trifluoromethyl-Phenyl)-Thiophene is a high-purity, specialized organic building block featuring a thiophene core linked to a trifluoromethylphenyl group. This molecular architecture is critical for imparting unique electronic and steric properties in advanced synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical sectors for creating novel active ingredients. The compound serves as a key intermediate in the development of compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Active Ingredient Synthesis: Used to develop novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances lipophilicity and biological activity.
• Material Science Research: Serves as a monomer or precursor in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create sophisticated ligands for catalysis, leveraging the electron-withdrawing character of the CF3 group.
• Fluorescent Probe and Dye Synthesis: The conjugated thiophene system makes it a valuable starting material for synthesizing specialized fluorophores and imaging agents.

Basic Information

Product Name	3-(3-Trifluoromethyl-Phenyl)-Thiophene
CAS No.	122159-58-4
Molecular Formula	C11H7F3S
Molecular Weight	228.23 g/mol
Synonyms	3-(3-(Trifluoromethyl)phenyl)thiophene; [3-(Trifluoromethyl)phenyl]thiophene; 3-(α,α,α-Trifluoro-m-tolyl)thiophene; m-(Trifluoromethyl)phenylthiophene; 3-(3-Trifluoromethylphenyl)thiophene; 3-(m-Trifluoromethylphenyl)thiophene; Thiophene, 3-[3-(trifluoromethyl)phenyl]-; 122159-58-4
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Trifluoromethyl-Phenyl)-Thiophene is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical R&D and scale-up processes. Our standard quality commitment includes rigorous purity verification via HPLC/GC, identity confirmation (IR, NMR), and control of specified impurities. Certificates of Analysis (COA) detailing all test results are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.