Description

1-[(2S)-2-(Benzyloxy)Propanoyl]Pyrrolidine is a chiral, non-racemic building block of significant interest in advanced organic synthesis. Its core value lies in its utility as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing bioactive compounds. This product is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly those focused on asymmetric synthesis and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) and antiviral drugs.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing sophisticated ligands used in enantioselective catalysis.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry impacts biological activity and environmental safety.
• Peptidomimetic Research: Employed in the design and synthesis of peptidomimetics and protease inhibitors due to its pyrrolidine scaffold and functional handles.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, enabling new routes to stereochemically complex architectures.
• Custom Synthesis Building Block: Provides a versatile chiral fragment for contract research organizations (CROs) and companies engaged in custom chemical synthesis.

Basic Information

Product Name	1-[(2S)-2-(Benzyloxy)Propanoyl]Pyrrolidine
CAS No.	122151-32-0
Molecular Formula	C14H19NO2
Molecular Weight	233.31 g/mol
Synonyms	(S)-1-(2-(Benzyloxy)propanoyl)pyrrolidine; L-Proline, 1-[(2S)-2-(phenylmethoxy)-1-oxopropyl]-; 1-[(2S)-2-(Benzyloxy)propionyl]pyrrolidine; (S)-2-(Benzyloxy)-N-(pyrrolidin-1-yl)propanamide; (S)-1-(2-(Benzyloxy)propanoyl)pyrrolidine; Pyrrolidine, 1-[(2S)-2-(benzyloxy)-1-oxopropyl]-; 122151-32-0; (S)-N-(2-(Benzyloxy)propanoyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our production of 1-[(2S)-2-(Benzyloxy)Propanoyl]Pyrrolidine adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity, which is paramount for its application in sensitive syntheses. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to maintain stability and purity over extended periods.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.