Description

Acetamide, n-[2-(3,4-Dioxo-1,5-Cyclohexadien-1-Yl)-2-Hydroxyethyl]-, (R)- (9Ci) is a specialized chiral acetamide derivative featuring a functionalized cyclohexadienone moiety, making it a valuable synthetic intermediate for advanced organic chemistry. This compound is critical for research and development in asymmetric synthesis and the creation of complex molecular architectures. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Utilized as a precursor or ligand in catalytic asymmetric reactions to induce chirality in target molecules.
• Fine Chemical Production: Serves as a starting material for the manufacture of complex, high-value specialty chemicals used in agrochemicals and materials science.
• Biochemical Research: Used in academic and industrial research to study enzyme inhibition or receptor-ligand interactions due to its specific stereochemistry and functional groups.
• Development of Molecular Probes: The reactive quinone-like structure makes it suitable for creating probes and tags for biochemical assays and diagnostics.

Basic Information

Product Name	Acetamide, n-[2-(3,4-Dioxo-1,5-Cyclohexadien-1-Yl)-2-Hydroxyethyl]-, (R)- (9Ci)
CAS No.	122121-93-1
Molecular Formula	C10H11NO4
Molecular Weight	209.20 g/mol
Synonyms	(R)-N-[2-(3,4-Dioxo-1,5-cyclohexadien-1-yl)-2-hydroxyethyl]acetamide; (R)-2-Acetamido-1-(3,4-dioxo-1,5-cyclohexadien-1-yl)ethanol; 1,5-Cyclohexadiene-1,4-dione, 1-[2-(acetylamino)-1-hydroxyethyl]-, (1R)-; (R)-1-(2-Acetamido-1-hydroxyethyl)-1,4-benzoquinone (tautomeric form); Chiral Acetamide Cyclohexadienone Derivative; R-Enantiomer of N-(2-Hydroxy-2-(3,4-dioxocyclohexa-1,5-dien-1-yl)ethyl)acetamide
EINECS	Contact for details

Quality Control

Our production of Acetamide, n-[2-(3,4-Dioxo-1,5-Cyclohexadien-1-Yl)-2-Hydroxyethyl]-, (R)- (9Ci) adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (e.e.) and chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.