Description

(R)-(+)-1-Benzyl-4-Hydroxy-2-Pyrrolidinone is a high-value chiral building block and intermediate of significant importance in asymmetric synthesis. Its core value lies in its stereochemically defined pyrrolidinone structure, which serves as a versatile scaffold for constructing complex, biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of novel active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands and organocatalysts for stereoselective chemical transformations.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, agrochemicals, and specialty chemicals requiring high stereochemical fidelity.
• Academic & R&D: Serves as a critical starting material in medicinal chemistry research and process development for new chemical entities.
• Peptidomimetics Development: Its structure is valuable for creating peptidomimetic compounds and conformationally constrained amino acid analogs.

Basic Information

Product Name	(R)-(+)-1-Benzyl-4-Hydroxy-2-Pyrrolidinone
CAS No.	122089-39-8
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	(R)-1-Benzyl-4-hydroxypyrrolidin-2-one; (R)-(+)-1-Benzyl-4-hydroxy-2-pyrrolidinone; (R)-4-Hydroxy-1-benzyl-2-pyrrolidinone; (R)-1-Benzyl-4-hydroxy-2-oxopyrrolidine; (R)-N-Benzyl-4-hydroxy-2-pyrrolidinone; (R)-4-Hydroxy-N-benzyl-2-pyrrolidinone; (R)-1-Benzyl-4-hydroxypyrrolidin-2-one; (R)-Benzyl-4-hydroxy-2-pyrrolidinone
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-Benzyl-4-Hydroxy-2-Pyrrolidinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including chiral purity verification, to meet the stringent requirements of advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.