Description

Maltose-Maleimide CAS NO 122018-89-7 is a specialized heterobifunctional crosslinking agent that combines the reducing sugar maltose with a maleimide functional group. This compound is critical for creating stable, site-specific conjugates between thiol-containing molecules and carbohydrates or other amine-reactive targets. It is primarily utilized by researchers and manufacturers in the bioconjugation, pharmaceutical development, and diagnostic sectors who require precise and efficient coupling strategies for proteins, peptides, and nanoparticles.

Application

• Bioconjugation Reagent: For the site-specific coupling of thiolated antibodies, proteins, or peptides to carbohydrate-based carriers, surfaces, or other amine-containing molecules.
• Drug Delivery System Development: Used in the synthesis of targeted drug conjugates, such as antibody-drug conjugates (ADCs), where a therapeutic payload is linked via a sugar spacer.
• Diagnostic Assay Development: Employed to label proteins or antibodies with enzymes, fluorophores, or other detection molecules for ELISA, lateral flow assays, or biosensors.
• Surface Functionalization: Modifying gold nanoparticles, quantum dots, or other nanomaterials with sugars for improved biocompatibility, targeting, or cellular uptake studies.
• Glycobiology Research: A tool for studying carbohydrate-protein interactions, lectin binding, and cell surface labeling.
• Polymer Chemistry: Serving as a functional monomer or crosslinker in the synthesis of smart hydrogels or biocompatible polymers with tailored reactivity.

Basic Information

Product Name	Maltose-Maleimide
CAS No.	122018-89-7
Molecular Formula	C16H23NO11
Molecular Weight	405.36 g/mol
Synonyms	4-Maleimidophenyl α-D-maltoside; Maltose-PDPH; N-(4-(α-D-Maltosyloxy)phenyl)maleimide; 1-[4-([(2R,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]oxy)phenyl]-1H-pyrrole-2,5-dione; Maltose Maleimide Crosslinker; Maleimide-functionalized Maltose
EINECS	Contact for details

Quality Control

Our Maltose-Maleimide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, appearance, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be kept under desiccant. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.