Description

Isovaline, 3-Fluoro-n-(Trifluoroacetyl)- (9Ci) is a specialized fluorinated derivative of the non-proteinogenic amino acid isovaline. This compound is of significant interest in advanced organic synthesis and pharmaceutical research, particularly as a key building block for the development of novel bioactive molecules and peptidomimetics. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate unique fluorinated motifs into their target compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the research and development of new drug candidates, especially those targeting neurological pathways or requiring metabolic stability.
• Agrochemical Research: Used in the synthesis of novel fluorinated pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Peptidomimetic Design: Acts as a constrained, fluorinated amino acid analog for creating stable peptide mimics with potential therapeutic applications.
• Chemical Biology Probe Development: Employed to synthesize labeled or modified compounds for studying enzyme mechanisms and protein interactions.
• Material Science Precursor: Can be utilized in the development of specialized fluorinated polymers or coatings with unique surface properties.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting fundamental research in synthetic methodology and fluorine chemistry.

Basic Information

Product Name	Isovaline, 3-Fluoro-n-(Trifluoroacetyl)- (9Ci)
CAS No.	122008-08-6
Molecular Formula	C7H9F4NO3
Molecular Weight	231.15 g/mol
Synonyms	3-Fluoro-N-(trifluoroacetyl)isovaline; 2-Amino-2-methylbutanoic acid, 3-fluoro-N-(trifluoroacetyl)-; N-(Trifluoroacetyl)-3-fluoroisovaline; 3-Fluoro-N-trifluoroacetylisovaline; (2R)-2-Amino-3-fluoro-2-methyl-N-(2,2,2-trifluoroacetyl)butanamide (stereoisomer); 122008-08-6; Isovaline derivative, fluorinated
EINECS	Contact for details

Quality Control

Our Isovaline, 3-Fluoro-n-(Trifluoroacetyl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.