Description

Isovaline, 3-Fluoro- (9Ci) is a fluorinated derivative of the non-proteinogenic amino acid isovaline, identified by CAS NO 122008-07-5. This compound is a valuable chiral building block and intermediate in advanced organic synthesis, particularly for introducing fluorine atoms into complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, especially for fluorinated analogs with potential enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atom can improve activity, selectivity, and environmental persistence.
• Peptidomimetics & Bioactive Molecule Design: Incorporated into peptide analogs and other bioactive compounds to study structure-activity relationships and modulate biological properties.
• Chemical Biology Research: Employed as a probe or building block in studying enzyme mechanisms, metabolic pathways, and protein-ligand interactions involving amino acid analogs.
• Material Science Precursor: Acts as a specialty monomer or functionalization agent for synthesizing advanced polymers and materials with specific surface properties.
• Asymmetric Synthesis Catalyst Ligand: Potential use in the development of chiral ligands or organocatalysts for enantioselective transformations.

Basic Information

Product Name	Isovaline, 3-Fluoro- (9Ci)
CAS No.	122008-07-5
Molecular Formula	C5H10FNO2
Molecular Weight	135.14 g/mol
Synonyms	3-Fluoroisovaline; (R,S)-3-Fluoro-2-amino-2-methylbutanoic acid; 2-Amino-3-fluoro-2-methylbutyric acid; DL-3-Fluoroisovaline; 3-Fluoro-2-aminoisovaleric acid; 3-Fluoro-2-amino-2-methylbutyric acid; (±)-3-Fluoroisovaline; 2-Methyl-3-fluoro-2-aminobutanoic acid
EINECS	Contact for details

Quality Control

Our Isovaline, 3-Fluoro- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric composition, and spectroscopic identification (NMR, IR, MS). A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.