Description

n-Acetyl-Gastrin Releasing Peptide (20-26) Ethyl Ester is a synthetic peptide fragment derived from the C-terminal region of the gastrin-releasing peptide (GRP). This compound is a critical biochemical tool for research into receptor-ligand interactions and signal transduction pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neurobiology, oncology, and gastrointestinal physiology.

Application

• Biochemical Research: As a specific ligand for studying the binding affinity and function of GRP receptors (GRPR) in vitro.
• Neuroscience Studies: Investigation of neurotransmitter release mechanisms and neural signaling pathways related to GRP.
• Cancer Research: Exploration of GRPR expression and its role in tumor cell proliferation, particularly in cancers like prostate and lung.
• Peptide Synthesis Intermediate: Used as a building block or precursor in the solid-phase or solution-phase synthesis of longer, modified GRP analogs.
• Diagnostic Development: Potential use in the development of assays or imaging probes targeting the GRP receptor.
• Pharmacological Profiling: Screening and characterization of potential GRPR antagonists or agonists in drug discovery programs.

Basic Information

Product Name	n-Acetyl-Gastrin Releasing Peptide (20-26) Ethyl Ester
CAS No.	122001-05-2
Molecular Formula	C44H66N12O11
Molecular Weight	939.1 g/mol
Synonyms	Acetyl-GRP (20-26) Ethyl Ester; N-Acetyl-GRP(20-26)-OEt; [Ac-Tyr-Pro-Arg-Leu-Gly-Asn-His]-OEt; Gastrin Releasing Peptide Fragment (20-26), N-acetyl-, ethyl ester; GRP (20-26) Ethyl Ester, N-Acetyl-; H-Ac-Tyr-Pro-Arg-Leu-Gly-Asn-His-OEt; Ac-Tyr-Pro-Arg-Leu-Gly-Asn-His-OEt; Ac-YPRLGNHEt
EINECS	Contact for details

Quality Control

Our n-Acetyl-Gastrin Releasing Peptide (20-26) Ethyl Ester is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles for manufacturing and our quality system is designed to meet the exacting standards of the global research community.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.