Description

(R)-2-Methoxymandelonitrile is a high-value chiral building block and intermediate in organic synthesis. This compound matters for its role in the stereoselective construction of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists for the synthesis of active pharmaceutical ingredients (APIs), fine chemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of enantiomerically pure drugs, including β-blockers and other cardiovascular agents.
• Agrochemical Synthesis: Used in the manufacture of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems for stereoselective transformations.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(R)-2-Methoxymandelonitrile
CAS No.	121985-99-7
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	(R)-α-Hydroxy-2-methoxybenzeneacetonitrile; (R)-2-Methoxy-2-phenylglycolonitrile; (R)-O-Methylmandelonitrile; (R)-Mandelonitrile 2-methyl ether; (R)-α-Methoxymandelonitrile; (R)-2-Methoxyphenylglycolonitrile; (R)-2-Methoxybenzyl cyanohydrin
EINECS	Contact for details

Quality Control

Our (R)-2-Methoxymandelonitrile is produced under strict quality control protocols to ensure high chemical and chiral purity. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess, and impurity profile. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.