Description

Benzeneacetonitrile, α-Hydroxy-4-(1-Methylethyl)-, (Alphar)- (9Ci) is a specialized organic compound featuring a benzeneacetonitrile core substituted with a hydroxy and an isopropyl group. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for fine chemical synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries to create complex target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for compounds requiring specific stereochemistry.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to synthesize novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Fine Chemical Production: Acts as a building block for dyes, pigments, and other high-value specialty chemicals.
• Academic and Industrial Research: Employed in chemical research for methodological studies and the exploration of new synthetic pathways.

Basic Information

Item	Details
Product Name	Benzeneacetonitrile, α-Hydroxy-4-(1-Methylethyl)-, (Alphar)- (9Ci)
CAS No.	121985-97-5
Molecular Formula	C11H13NO
Molecular Weight	175.23 g/mol
Synonyms	α-Hydroxy-4-isopropylbenzeneacetonitrile; (αR)-α-Hydroxy-4-(1-methylethyl)benzeneacetonitrile; (R)-2-Hydroxy-2-(4-isopropylphenyl)acetonitrile; 4-Isopropylmandelonitrile; (R)-4-Isopropylmandelonitrile; (R)-2-(4-Isopropylphenyl)-2-hydroxyacetonitrile; Alphar-hydroxy-4-isopropylbenzeneacetonitrile
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile, α-Hydroxy-4-(1-Methylethyl)-, (Alphar)- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.