Description

1,2-Bis(Di-tert-Butylphosphinomethyl)Benzene CAS NO 121954-50-5 is a specialized, high-value organophosphorus ligand used in advanced catalytic processes. Its primary value lies in its ability to form highly active and selective metal complexes, particularly for challenging cross-coupling and hydrogenation reactions. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require precise control over reaction stereochemistry and yield.

Application

• Homogeneous Catalysis: As a key ligand for palladium, nickel, and rhodium catalysts in C-C and C-N cross-coupling reactions (e.g., Suzuki, Heck, Buchwald-Hartwig).
• Asymmetric Synthesis: Enabling enantioselective hydrogenation and other transformations for the production of chiral intermediates in active pharmaceutical ingredients (APIs).
• Polymerization Catalysis: Used in the development of novel coordination catalysts for olefin polymerization and copolymerization.
• Material Science Research: A building block for creating novel phosphine-based frameworks and functional materials.
• Agrochemical Intermediate Synthesis: Facilitating the production of complex, high-performance molecules through efficient catalytic steps.
• Academic & Industrial R&D: A critical tool for exploring new catalytic methodologies and reaction pathways in laboratory-scale and pilot-scale research.

Basic Information

Product Name	1,2-Bis(Di-tert-Butylphosphinomethyl)Benzene
CAS No.	121954-50-5
Molecular Formula	C26H48P2
Molecular Weight	422.60 g/mol
Synonyms	1,2-Bis[(di-tert-butylphosphino)methyl]benzene; DtBPMB; Di-tert-Butylphosphinomethyl Benzene Derivative; (o-Xylylene)bis(di-tert-butylphosphine); 1,2-Bis(di-tert-butylphosphanylmethyl)benzene; BIS(DI-TERT-BUTYLPHOSPHINOMETHYL)BENZENE; DTBPMB Ligand
EINECS	Contact for details

Quality Control

Every batch of 1,2-Bis(Di-tert-Butylphosphinomethyl)Benzene is manufactured and handled under strict quality protocols to ensure consistency and reliability for sensitive catalytic applications. Our products undergo rigorous quality testing, including advanced spectroscopic analysis, to ensure compliance with stringent purity standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should only be opened in an inert glovebox or under a positive pressure of inert gas.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
31P NMR	Conforms to reference spectrum
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.