Description

1H-Pyrrole-2-Acetonitrile, 1-Acetyl-α-Hydroxy-, (R)- (9Ci) is a high-purity, chiral pyrrole derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block for the development of complex molecules, particularly in the pharmaceutical sector. It is primarily sought after by research and development teams in fine chemical, agrochemical, and pharmaceutical industries for the synthesis of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct complex molecular architectures with defined chirality.
• Agrochemical Research: Serves as a precursor in the development of new, more effective crop protection agents and pesticides.
• Material Science: Investigated for the synthesis of specialized polymers and organic electronic materials due to its pyrrole core.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	1H-Pyrrole-2-Acetonitrile, 1-Acetyl-α-Hydroxy-, (R)- (9Ci)
CAS No.	121950-16-1
Molecular Formula	C8H8N2O2
Molecular Weight	164.16 g/mol
Synonyms	(R)-1-Acetyl-α-hydroxy-1H-pyrrole-2-acetonitrile; 1-Acetyl-α-hydroxy-1H-pyrrole-2-acetonitrile, (R)-; 2-(1-Acetyl-2-hydroxy-1H-pyrrol-2-yl)acetonitrile; (R)-1-Acetyl-2-(cyanomethyl)-2-hydroxy-2,5-dihydro-1H-pyrrole; 1-Acetyl-α-hydroxy-1H-pyrrole-2-acetonitrile (R-enantiomer)
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrole-2-Acetonitrile, 1-Acetyl-α-Hydroxy-, (R)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure consistency and meet the exacting standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.