Description

(R)-1,2-Bis(Diphenylphosphino)Cyclohexylethane CAS NO 121902-84-9 is a high-value, chiral bisphosphine ligand widely utilized in asymmetric catalysis. Its primary value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, which is critical for producing optically pure intermediates and active pharmaceutical ingredients (APIs). This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and effective chiral auxiliaries for complex synthetic routes.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiomerically pure amino acids and pharmaceutical intermediates.
• Catalyst component for asymmetric C-C bond-forming reactions, including cross-coupling and allylic substitution.
• Key reagent in the development of novel catalytic systems for academic and industrial research in organic synthesis.
• Used in the production of chiral agrochemicals and flavors & fragrances where optical purity is mandated.
• Employed in the synthesis of complex natural products and specialty chemicals requiring high stereocontrol.

Basic Information

Product Name	(R)-1,2-Bis(Diphenylphosphino)Cyclohexylethane
CAS No.	121902-84-9
Molecular Formula	C32H34P2
Molecular Weight	480.56 g/mol
Synonyms	(R)-Cyclohexane-1,2-diylbis(diphenylphosphine); (R)-Cyclohexyl-Bis(diphenylphosphino)ethane; (R)-Cyclohexyl-BDPE; (R)-Bis(diphenylphosphino)cyclohexylethane; (R)-Cyclohexyl-DIPHOS; (R)-Cyclohexyl-Bisphosphine Ligand; (R)-Cyclohexyl-BDPCE; (R)-1,2-Bis(diphenylphosphino)-1,2-dicyclohexylethane (common misnomer)
EINECS	Contact for details

Quality Control

Our (R)-1,2-Bis(Diphenylphosphino)Cyclohexylethane is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chiral purity, which is critical for catalytic performance. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and other critical parameters is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided to maintain efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.