Description

5-Fluoro-3-Pentafluoroethyl-1-Phenyl-4-Trifluoromethyl-1H-Pyrazole is a highly fluorinated pyrazole derivative, a specialized chemical building block prized for its unique electronic and steric properties imparted by the perfluoroalkyl groups. This compound matters for its critical role in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure can significantly alter solubility, metabolic stability, and binding affinity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas requiring fluorinated motifs for improved bioavailability and metabolic stability.
• Agrochemical Research: Used in the synthesis of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to desirable dielectric and optical properties.
• Polymer & Coating Modifier: Incorporated into specialty polymers to impart oil- and water-repellency (similar to fluorosurfactants) and chemical resistance.
• Catalyst Ligand Synthesis: The pyrazole core can be functionalized to create novel ligands for transition metal catalysis in fine chemical synthesis.
• Chemical Research & Development: A versatile building block for exploring structure-activity relationships (SAR) in medicinal and materials chemistry.

Basic Information

Item	Details
Product Name	5-Fluoro-3-Pentafluoroethyl-1-Phenyl-4-Trifluoromethyl-1H-Pyrazole
CAS No.	121807-33-8
Molecular Formula	C12H4F9N2
Molecular Weight	356.16 g/mol
Synonyms	1-Phenyl-5-fluoro-3-(pentafluoroethyl)-4-(trifluoromethyl)-1H-pyrazole; 5-Fluoro-3-(pentafluoroethyl)-1-phenyl-4-(trifluoromethyl)pyrazole; 1H-Pyrazole, 5-fluoro-3-(pentafluoroethyl)-1-phenyl-4-(trifluoromethyl)-; 5-Fluoro-3-pentafluoroethyl-1-phenyl-4-trifluoromethylpyrazole
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-Pentafluoroethyl-1-Phenyl-4-Trifluoromethyl-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.