Description

(S,S)-N,N'-Bis(Trifluoromethanesulfonyl)-1,2-Diphenylethylenediamine is a high-value, chiral bis(triflyl) amide derivative of a 1,2-diaminoethane scaffold. This compound matters as a sophisticated chiral ligand and catalyst precursor, enabling highly enantioselective transformations critical for producing single-isomer pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for asymmetric synthesis.

Application

• Asymmetric Catalysis: Serving as a chiral ligand or precursor for metal complexes (e.g., with Cu, Pd, Fe) in enantioselective C–H activation, cycloaddition, and cross-coupling reactions.
• Pharmaceutical Intermediate Synthesis: A key building block or chiral auxiliary in the multi-step synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Chiral Resolution Agent: Used in the development of methods for the separation of racemic mixtures of acids or amines via diastereomeric salt formation.
• Organocatalysis: Potential application as a bifunctional organocatalyst in reactions where its strong electron-withdrawing triflyl groups and chiral diamine structure can activate substrates.
• Material Science Research: Investigation as a component in chiral polymers or metal-organic frameworks (MOFs) for enantioselective sensing or separation.
• Methodology Development: A valuable reagent in academic and industrial research labs for developing new enantioselective synthetic methodologies.

Basic Information

Product Name	(S,S)-N,N'-Bis(Trifluoromethanesulfonyl)-1,2-Diphenylethylenediamine
CAS No.	121788-77-0
Molecular Formula	C₁₆H₁₄F₆N₂O₄S₂
Molecular Weight	476.41 g/mol
Synonyms	(S,S)-N,N'-Bis(triflyl)-1,2-diphenylethylenediamine; (S,S)-1,2-Diphenyl-N,N'-bis[(trifluoromethyl)sulfonyl]ethane-1,2-diamine; (S,S)-DPEN-Tf₂; (S,S)-Bis(trifluoromethanesulfonyl)-1,2-diphenylethylenediamine; (S,S)-Ethylenediamine, N,N'-bis[(trifluoromethyl)sulfonyl]-1,2-diphenyl-; (S,S)-Jacobsen's Ligand Tf Derivative; (S,S)-Bis(triflyl)DPEN
EINECS	Contact for details

Quality Control

Our (S,S)-N,N'-Bis(Trifluoromethanesulfonyl)-1,2-Diphenylethylenediamine is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification. Certificates of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment, ideally under an inert atmosphere for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.