Description

5-Bromo-1,1,1-Trifluoropentane-2-One is a versatile fluorinated building block and key intermediate in advanced organic synthesis. This compound is valued for its unique trifluoromethyl and bromo functional groups, which enable precise molecular modifications and the introduction of fluorine atoms to enhance the properties of target molecules. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials industries for applications in drug discovery, crop protection, and the development of novel fluorinated polymers.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethyl groups to improve metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine moiety enhances biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or precursor in the development of specialty fluoropolymers and advanced materials with unique surface properties, chemical resistance, and thermal stability.
• Liquid Crystal & OLED Materials: Employed in the synthesis of fluorinated components for electronic displays and organic light-emitting diodes (OLEDs) to optimize performance and efficiency.
• Cross-Coupling Reactions: Acts as a valuable electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) for constructing complex, fluorinated aromatic and heteroaromatic systems.
• Fluorine Chemistry Research: A key reagent in academic and industrial laboratories for exploring new methodologies in organofluorine chemistry and asymmetric synthesis.

Basic Information

Product Name	5-Bromo-1,1,1-Trifluoropentane-2-One
CAS No.	121749-67-5
Molecular Formula	C5H6BrF3O
Molecular Weight	219.00 g/mol
Synonyms	1-Bromo-4,4,4-trifluorobutan-2-one; 4,4,4-Trifluoro-1-bromobutan-2-one; 5-Bromo-1,1,1-trifluoropentan-2-one; 4-Bromo-1,1,1-trifluorobutan-2-one; 2-Pentanone, 5-bromo-1,1,1-trifluoro-; 5-Bromo-1,1,1-trifluoro-2-pentanone
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,1,1-Trifluoropentane-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are sealed under an inert atmosphere such as nitrogen to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.