Description

2-Pentanone, 3,3-Difluoro-5-Hydroxy- (9Ci) is a specialized fluorinated ketone building block with a reactive hydroxyl group, offering unique synthetic versatility. This compound is valued for its ability to introduce both fluorine atoms and a functional handle for further derivatization into complex molecular architectures. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, potentially enhancing metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, or insecticides where the difluoro and hydroxy motifs can influence biological activity and environmental fate.
• Advanced Material Precursor: Serves as a monomer or modifying agent in the synthesis of specialty polymers and coatings with tailored surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create chelating ligands for catalysis or metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable tool in academic and industrial R&D for studying the effects of fluorine substitution on chemical reactivity and physical properties.
• Fine Chemical Production: Incorporated into the multi-step synthesis of complex fluorinated fine chemicals and flavors & fragrances.

Basic Information

Item	Detail
Product Name	2-Pentanone, 3,3-Difluoro-5-Hydroxy- (9Ci)
CAS No.	121749-56-2
Molecular Formula	C5H8F2O2
Molecular Weight	138.11 g/mol
Synonyms	3,3-Difluoro-5-hydroxypentan-2-one; 5-Hydroxy-3,3-difluoropentan-2-one; 1,1-Difluoro-4-hydroxy-3-butanone; 3,3-Difluoro-5-hydroxy-2-pentanone; 1,1-Difluoro-4-hydroxybutan-3-one; Difluorohydroxypentanone
EINECS	Contact for details

Quality Control

Every batch of 2-Pentanone, 3,3-Difluoro-5-Hydroxy- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets your research and development specifications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by GC/HPLC), identity confirmation, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain product integrity. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥95.0% (Research Grade)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.