Description

2-Butanone, 3,3-Difluoro-4-Hydroxy- (9Ci) is a specialized fluorinated ketone building block, identified by CAS number 121749-55-1. This compound is valued for its unique molecular structure, which incorporates both a ketone and a hydroxyl group adjacent to difluoromethylene units, making it a versatile intermediate for introducing fluorine into complex molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and advanced agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where fluorine atoms can enhance biological activity and environmental stability.
• Advanced Material Precursor: Serves as a building block for fluorinated polymers, liquid crystals, or specialty coatings with tailored surface properties.
• Organic Synthesis & Catalysis: Employed in academic and industrial research for developing new fluorination methodologies and asymmetric synthesis routes.
• Chemical Biology Probes: Useful in the design of fluorinated probes and tags for studying biological mechanisms and diagnostics.

Basic Information

Product Name	2-Butanone, 3,3-Difluoro-4-Hydroxy- (9Ci)
CAS No.	121749-55-1
Molecular Formula	C4H6F2O2
Molecular Weight	124.09 g/mol
Synonyms	3,3-Difluoro-4-hydroxybutan-2-one; 4-Hydroxy-3,3-difluorobutan-2-one; 1,1-Difluoro-3-hydroxy-2-butanone; 3,3-Difluoro-4-hydroxy-2-butanone; 2-Butanone, 3,3-difluoro-4-hydroxy-
EINECS	Contact for details

Quality Control

Our 2-Butanone, 3,3-Difluoro-4-Hydroxy- (9Ci) is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, assay, and impurity profiles. We support cGMP-compliant production for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.