Description

n-α-Cbz-Glycine n-Methoxy-n-Methylamide is a protected glycine derivative widely used as a key synthetic intermediate in organic and medicinal chemistry. This compound is crucial for constructing peptide backbones and other complex molecules, offering controlled reactivity for advanced synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Peptide Synthesis: Serves as a crucial building block for the controlled introduction of glycine residues in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Used in the research and development of novel therapeutic compounds, including protease inhibitors and other biologically active peptides.
• Chemical Biology Probes: Acts as a precursor for synthesizing labeled or modified amino acid derivatives used in biochemical and cellular studies.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening in drug discovery programs.
• Fine Chemical Production: Utilized as a specialized intermediate in the custom synthesis of complex organic molecules for various industrial applications.
• Academic Research: A valuable reagent for methodological development in organic synthesis and for studying reaction mechanisms involving amide bonds.

Basic Information

Product Name	n-α-Cbz-Glycine n-Methoxy-n-Methylamide
CAS No.	121505-94-0
Molecular Formula	C13H18N2O4
Molecular Weight	266.29 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]glycine N-methoxy-N-methylamide; Cbz-Glycine Weinreb Amide; N-Carbobenzoxyglycine N,O-Dimethylhydroxylamine; (Benzyloxycarbonyl)glycine N-methoxy-N-methylamide; Z-Gly-ONHMe(OMe); Z-Gly-N(OMe)Me; Glycine, N-[(phenylmethoxy)carbonyl]-, N-methoxy-N-methylamide; Nα-Cbz-glycine N-methoxy-N-methylamide
EINECS	Contact for details

Quality Control

Our n-α-Cbz-Glycine n-Methoxy-n-Methylamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.