Description

(R)-(+)-2,2'-Bis(Dicyclohexylphosphino)-1,1'-Binaphthyl CAS NO 121457-42-9 is a high-value, chiral bisphosphine ligand widely recognized for its exceptional performance in asymmetric catalysis. Its primary value lies in enabling highly enantioselective transformations, which are critical for the efficient synthesis of single-enantiomer pharmaceuticals and fine chemicals. This product is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable and effective ligands for challenging asymmetric hydrogenation and cross-coupling reactions.

Application

• As a privileged ligand for asymmetric hydrogenation of olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Catalyst component for enantioselective cross-coupling reactions, including Suzuki-Miyaura and Heck reactions.
• Key chiral inducer in the synthesis of active pharmaceutical ingredients (APIs) and natural products.
• Research and development of novel homogeneous catalysts for academic and industrial discovery programs.
• Production of electronic chemicals and advanced materials requiring precise chiral control.
• Process development and scale-up in fine chemical and agrochemical manufacturing.

Basic Information

Product Name	(R)-(+)-2,2'-Bis(Dicyclohexylphosphino)-1,1'-Binaphthyl
CAS No.	121457-42-9
Molecular Formula	C44H56P2
Molecular Weight	646.86 g/mol
Synonyms	(R)-(+)-2,2'-Bis(dicyclohexylphosphino)-1,1'-binaphthyl; (R)-2,2'-Bis(dicyclohexylphosphino)-1,1'-binaphthyl; (R)-DCB; (R)-BINAP(Dicyclohexyl); (R)-2,2'-Bis(dicyclohexylphosphino)-1,1'-binaphthalene; (R)-Bis(dicyclohexylphosphino)binaphthyl; (R)-Dicyclohexyl-BINAP; (R)-BINAP(DC)
EINECS	Contact for details

Quality Control

Our (R)-(+)-2,2'-Bis(Dicyclohexylphosphino)-1,1'-Binaphthyl is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized using advanced analytical techniques, including NMR, HPLC, and chiral analysis, to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should only be opened in an inert environment.

Specification

Item	Specification
Appearance	White to off-white powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.