Description

Ethanone, 1-(2,6-Dimethylphenyl)-2,2,2-Trifluoro- (9Ci) is a specialized trifluoromethyl ketone derivative, a high-value building block prized for its unique structural motif. This compound matters for its role in facilitating the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research where the introduction of a trifluoromethyl group is critical for modulating biological activity and metabolic stability. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate this potent fluorinated moiety into novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological efficacy.
• Ligand and Catalyst Precursor: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research and development of specialty polymers and liquid crystals with tailored optical and electronic properties.
• Fluorine Chemistry Studies: An important reference compound and reactant in academic and industrial research focused on fluorination methodologies and the study of fluorine effects.

Basic Information

Product Name	Ethanone, 1-(2,6-Dimethylphenyl)-2,2,2-Trifluoro- (9Ci)
CAS No.	121456-63-1
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	1-(2,6-Dimethylphenyl)-2,2,2-trifluoroethanone; 2,6-Dimethyl-α,α,α-trifluoroacetophenone; 2',6'-Dimethyl-2,2,2-trifluoroacetophenone; α,α,α-Trifluoro-2,6-dimethylacetophenone; 2,2,2-Trifluoro-1-(2,6-dimethylphenyl)ethanone; TFAP-DM; 2,6-Dimethyltrifluoroacetophenone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2,6-Dimethylphenyl)-2,2,2-Trifluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.