Description

Cefprozil (Z)-Isomer (200 Mg)H0E054927Ug/Mg(Ai) CAS NO 121412-77-9 is a high-purity, specific stereoisomer of the broad-spectrum cephalosporin antibiotic Cefprozil. This compound is of critical importance for pharmaceutical research and development, particularly in the study of structure-activity relationships, metabolic pathways, and the synthesis of advanced active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on antibiotic development, analytical method validation, and impurity profiling.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity testing of Cefprozil in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key chiral building block in the sophisticated synthesis of Cefprozil and related cephalosporin antibiotics.
• Metabolite and Impurity Studies: Essential for investigating the pharmacokinetics, degradation pathways, and stability profiles of Cefprozil-based drug products.
• Analytical Method Development: Employed to develop and validate high-performance liquid chromatography (HPLC) and other chromatographic methods for isomer separation and quantification.
• Pharmacological Research: Utilized in preclinical studies to understand the distinct biological activity and efficacy of the (Z)-isomer compared to other stereoisomers.
• Regulatory Compliance and Documentation: Supports regulatory filings (e.g., with FDA, EMA) by providing well-characterized materials for impurity identification and control strategies.

Basic Information

Product Name	Cefprozil (Z)-Isomer (200 Mg)H0E054927Ug/Mg(Ai) CAS NO 121412-77-9
CAS No.	121412-77-9
Molecular Formula	C18H19N3O5S
Molecular Weight	389.43 g/mol
Synonyms	(6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(Z)-1-propenyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (Z)-Cefprozil; Cefprozil Z-Isomer; Cefprozil Impurity; Cefprozil Related Compound; (Z)-Isomer of Cefprozil; Antibiotic Cefprozil Isomer
EINECS	Contact for details

Quality Control

Our Cefprozil (Z)-Isomer is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment. We support compliance with ICH guidelines and relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Z-Isomer)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.