Description

Angiotensin II Antipeptide is a specialized synthetic peptide designed to act as a selective antagonist of the Angiotensin II receptor. This compound is of significant value in cardiovascular and renal research for its ability to block the physiological effects of Angiotensin II, a key hormone in the renin-angiotensin system. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers for investigating hypertension, heart failure, and related metabolic disorders.

Application

• Pharmacological Research: Used as a critical tool compound for studying the role of the renin-angiotensin-aldosterone system (RAAS) in cardiovascular diseases.
• Biochemical Assay Development: Serves as a reference standard or competitive inhibitor in receptor binding assays and enzyme activity tests.
• Drug Discovery & Screening: Employed in high-throughput screening (HTS) platforms to identify and validate new Angiotensin II receptor blockers (ARBs).
• Academic & Clinical Studies: Facilitates in vitro and in vivo research on hypertension, cardiac hypertrophy, renal function, and vascular biology.
• Diagnostic Reagent Component: May be incorporated into specialized diagnostic kits for research purposes to measure Angiotensin II pathway activity.

Basic Information

Product Name	Angiotensin II Antipeptide
CAS No.	121379-63-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Angiotensin II Inhibitor; Angiotensin II Receptor Antagonist (Research Peptide); AT1 Receptor Antipeptide; Saralasin Analogue; [Sar¹, Ile⁸]-Angiotensin II (related antagonist); RAAS Inhibitor Peptide; AII Antipeptide
EINECS	Contact for details

Quality Control

Our Angiotensin II Antipeptide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including purity assessment by HPLC and structural confirmation by mass spectrometry, to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 5.0%
Peptide Content	≥ 80% (by weight)
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.