Description

5-Acetyl-2-Chloro-6-Methylnicotinonitrile is a versatile and high-value pyridine derivative used as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its functionalized pyridine core.
• Material Science Research: Serves as a precursor for the development of advanced organic materials, including ligands for catalysis and components for organic electronics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Acetyl-2-Chloro-6-Methylnicotinonitrile
CAS No.	121348-15-0
Molecular Formula	C9H7ClN2O
Molecular Weight	194.62 g/mol
Synonyms	2-Chloro-6-methyl-5-acetylnicotinonitrile; 5-Acetyl-2-chloro-6-methyl-3-cyanopyridine; 3-Cyano-2-chloro-6-methyl-5-acetylpyridine; 2-Chloro-5-acetyl-6-methyl-3-pyridinecarbonitrile; 121348-15-0; 5-Acetyl-2-chloro-6-methylpyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Acetyl-2-Chloro-6-Methylnicotinonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality system is designed to meet the stringent requirements of our global B2B partners in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.