Description

Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 is a synthetic peptide derivative, often utilized as a specialized biochemical tool in research and development. Its value lies in its role as a substrate or inhibitor for studying protease activity and enzyme kinetics, providing critical insights into biological pathways. This compound is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on drug discovery and proteomics.

Application

• Protease/Enzyme Research: Used as a specific chromogenic or fluorogenic substrate to assay the activity of various proteolytic enzymes.
• Drug Discovery Screening: Serves as a key biochemical tool in high-throughput screening (HTS) assays to identify potential therapeutic inhibitors.
• Biochemical Mechanism Studies: Employed to investigate enzyme specificity, catalytic mechanisms, and inhibition kinetics in vitro.
• Peptide Chemistry Reference Standard: Acts as a high-purity reference material for analytical method development and validation in peptide synthesis.
• Academic & Institutional Research: Supports fundamental research in biochemistry, molecular biology, and medicinal chemistry departments.

Basic Information

Item	Details
Product Name	Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2
CAS No.	121282-17-5
Molecular Formula	C53H74N16O12
Molecular Weight	1095.25 g/mol
Synonyms	Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-amide; Dnp-PLGLWA-DR-NH2; 2,4-Dinitrophenyl-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-amide; Chromogenic Peptide Substrate; Protease Substrate 121282-17-5; N-2,4-DNP-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2; H-Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including HPLC and mass spectrometry to verify identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, containers should be allowed to equilibrate to room temperature before opening to prevent condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.