Description

Terikalant is a high-purity, small-molecule chemical compound with the CAS number 121277-96-1. This compound is valued in advanced research and development for its specific pharmacological activity as a selective inhibitor. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on cardiac electrophysiology and antiarrhythmic drug discovery.

Application

• Pharmaceutical Research & Development: A key tool compound for investigating atrial-selective ion channel inhibition and cardiac electrophysiology.
• Preclinical Studies: Used in in vitro and in vivo models to study mechanisms for the treatment of atrial fibrillation and other arrhythmias.
• Biochemical Assays: Serves as a reference standard and active agent in high-throughput screening (HTS) and patch-clamp experiments targeting specific potassium channels.
• Academic Research: Employed in university and institutional labs for fundamental cardiovascular research and the validation of new therapeutic targets.
• Drug Discovery Programs: Integral to lead optimization and structure-activity relationship (SAR) studies for novel antiarrhythmic agents.

Basic Information

Product Name	Terikalant
CAS No.	121277-96-1
Molecular Formula	C21H28N4O3S
Molecular Weight	416.54 g/mol
Synonyms	Terikalant; N-[2-(4-Methoxyphenyl)ethyl]-N-methyl-2-[[(2S)-2-[[[3-(trifluoromethyl)phenyl]sulfonyl]amino]propanoyl]amino]acetamide; IKACh Blocker; IK,ACh Blocker; IKACH Blocker; HMR 1556; HMR1556; Ventricular Fibrillation Inhibitor HMR 1556
EINECS	Contact for details

Quality Control

Our Terikalant is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets the stringent requirements of research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.