Description

3,3,3-Trifluoro-1-(4-Methoxyphenyl)Propan-1-One is a high-value fluorinated aromatic ketone building block, essential for introducing the trifluoromethyl group into complex molecular architectures. Its unique structure, combining a methoxyphenyl moiety with a trifluoropropanone chain, makes it a critical intermediate in advanced organic synthesis. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Liquid Crystal Materials: Serves as a precursor for fluorinated compounds used in the electronics industry for liquid crystal displays (LCDs).
• Organic Light-Emitting Diodes (OLEDs): Acts as an intermediate in the production of electron-transport materials and emitters for high-performance OLED devices.
• Advanced Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and specialty chemicals with tailored properties.
• Fluorine Chemistry Studies: A valuable reference compound and starting material for methodological development in organofluorine chemistry.

Basic Information

Product Name	3,3,3-Trifluoro-1-(4-Methoxyphenyl)Propan-1-One
CAS No.	121194-35-2
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	1-(4-Methoxyphenyl)-3,3,3-trifluoropropan-1-one; 4'-Methoxy-3,3,3-trifluoropropiophenone; 3,3,3-Trifluoro-1-(4-methoxyphenyl)-1-propanone; 4-Methoxyphenyl 3,3,3-trifluoropropyl ketone; 3,3,3-Trifluoropropiophenone 4'-methyl ether; TFMPK-OMe; p-Methoxy-α,α,α-trifluoropropiophenone
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoro-1-(4-Methoxyphenyl)Propan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.