Description

Connexin 38 CAS NO 121127-32-0 is a specific connexin protein isoform, a key component of gap junction channels that facilitate direct intercellular communication. This compound is of significant value for researchers investigating cellular physiology, signal transduction, and tissue homeostasis. It is primarily needed by the life science research sector, including academic institutions, biotechnology firms, and pharmaceutical R&D departments focused on cell biology, neuroscience, and cardiology.

Application

• Biomedical Research: Fundamental studies on gap junction structure, function, and regulation.
• Neuroscience: Investigation of electrical synapse formation and neuronal network synchronization.
• Cardiovascular Research: Exploration of cardiac myocyte coupling and impulse propagation mechanisms.
• Developmental Biology: Analysis of cell-cell communication during embryogenesis and tissue patterning.
• Target Identification: Used in assays to screen for modulators of connexin-based channels for potential therapeutic applications.
• Reagent Production: Serves as an antigen for the generation of specific antibodies or as a standard in protein quantification assays.

Basic Information

Product Name	Connexin 38
CAS No.	121127-32-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Connexin-38; Cx38; Gap Junction β-5 Protein; GJB5; Human Connexin 38; Connexin 38 Protein; Recombinant Connexin 38; CX38 Protein
EINECS	Contact for details

Quality Control

Our Connexin 38 is produced and handled under stringent quality management protocols to ensure batch-to-batch consistency and biological activity. Each lot undergoes comprehensive analytical characterization, including purity assessment and functional validation where applicable. A detailed Certificate of Analysis (COA) documenting identity, purity, and other relevant parameters is provided with every shipment to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake. Aliquot reconstituted material to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Corresponds to expected molecular weight
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 95% of total mass
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Assay-dependent; Contact for details
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.