Description

4-(1,1'-Biphenyl-4-Yl)-5-(2-(4-Phenyl-1-Piperazinyl)Ethyl)-2(3H)-Oxazolone Dihydrochloride is a high-purity, complex organic salt primarily utilized as a critical intermediate in advanced pharmaceutical research and development. This compound is valued for its specific molecular architecture, which makes it a key building block in the synthesis of novel therapeutic agents targeting central nervous system disorders. It is essential for research chemists and process development scientists in the pharmaceutical and biotechnology industries. Our supply is characterized by stringent quality control to ensure batch-to-batch consistency for reliable experimental and scale-up outcomes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with neurological or psychiatric activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique biphenyl-piperazine-oxazolone scaffold.
• Process Chemistry Development: Serves as a standardized building block for developing and scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: May be utilized in vitro to study specific receptor interactions or enzymatic pathways in pharmacological research.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and validation in quality control laboratories.
• Custom Synthesis Starting Material: Provides a complex, functionalized core for the contract synthesis of specialized compounds for client-specific R&D projects.

Basic Information

Product Name	4-(1,1'-Biphenyl-4-Yl)-5-(2-(4-Phenyl-1-Piperazinyl)Ethyl)-2(3H)-Oxazolone Dihydrochloride
CAS No.	120944-30-1
Molecular Formula	C33H32N4O2 · 2HCl
Molecular Weight	613.56 g/mol (Free base: 540.64 g/mol)
Synonyms	4-(Biphenyl-4-yl)-5-[2-(4-phenylpiperazin-1-yl)ethyl]-4,5-dihydro-1,3-oxazol-2-one dihydrochloride; 2(3H)-Oxazolone, 4-(1,1'-biphenyl-4-yl)-5-[2-(4-phenyl-1-piperazinyl)ethyl]-, dihydrochloride; Biphenyl-oxazolone-piperazine dihydrochloride; 120944-30-1; CAS 120944-30-1
EINECS	Contact for details

Quality Control

Every batch of 4-(1,1'-Biphenyl-4-Yl)-5-(2-(4-Phenyl-1-Piperazinyl)Ethyl)-2(3H)-Oxazolone Dihydrochloride is manufactured and analyzed under a strict quality management system. We provide comprehensive analytical data to support its use in regulated environments. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment. Our quality protocols are designed to meet the exacting standards of pharmaceutical R&D, ensuring reliable and reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.