Description

[1(R)-Trans]-α-[[[4-(1-Methylethyl)Cyclohexyl]Carbonyl]Amino]Benzenepropanamide is a high-purity, stereochemically defined organic compound used as a key intermediate in advanced chemical synthesis. Its precise chiral structure makes it valuable for research and development in creating molecules with specific biological activity. This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel therapeutic agents and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological or metabolic pathways.
• Chiral Catalyst Research: Used in the study and development of asymmetric synthesis catalysts due to its defined stereochemistry.
• Medicinal Chemistry: Serves as a core scaffold or precursor for structure-activity relationship (SAR) studies in drug discovery programs.
• Reference Standard: Employed as an analytical standard in HPLC or LC-MS methods for quality control and impurity profiling in related chemical processes.
• Peptidomimetic Research: Its amide-based structure makes it suitable for research into peptidomimetics and bioisosteres.
• Fine Chemical Synthesis: An intermediate for the production of other complex, high-value specialty chemicals used in agrochemicals or material science.

Basic Information

Product Name	[1(R)-Trans]-α-[[[4-(1-Methylethyl)Cyclohexyl]Carbonyl]Amino]Benzenepropanamide
CAS No.	120927-39-1
Molecular Formula	C19H28N2O2
Molecular Weight	316.44 g/mol
Synonyms	(R)-N-[(4-Isopropylcyclohexyl)carbonyl]-3-phenylalaninamide; (R)-N-[(trans-4-Isopropylcyclohexyl)carbonyl]-3-phenylalaninamide; (R)-N-[(4-(1-Methylethyl)cyclohexyl)carbonyl]-3-phenylalaninamide; (R)-N-[(4-Isopropylcyclohexyl)carbonyl]-L-phenylalaninamide; (R)-N-[(4-Isopropylcyclohexyl)carbonyl]-β-phenylalanine amide; (R)-N-[(4-Isopropylcyclohexyl)carbonyl]-3-phenylalanine amide; (R)-N-[(4-Isopropylcyclohexyl)carbonyl]-3-phenylalanineamide; (R)-N-[(4-Isopropylcyclohexyl)carbonyl]-DL-phenylalaninamide
EINECS	Contact for details

Quality Control

Our [1(R)-Trans]-α-[[[4-(1-Methylethyl)Cyclohexyl]Carbonyl]Amino]Benzenepropanamide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.