Description

L-Tyr-D-Ala-Gly-n-[(1S)-3-Methyl-1-[[(3-Nitro-2-Pyridinyl)Dithio]Methyl]Butyl]-L-Phe-Nh2 is a specialized synthetic peptide derivative designed for advanced research and development applications. This compound is of significant interest due to its unique structure, which incorporates a cleavable disulfide linker, making it a valuable tool in targeted drug delivery and bioconjugation strategies. It is primarily utilized by pharmaceutical researchers and biotech companies engaged in the development of novel therapeutics, particularly in the fields of oncology and targeted diagnostics.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel peptide-based therapeutics.
• Targeted Drug Delivery Systems: The cleavable disulfide bond enables its use as a linker in antibody-drug conjugates (ADCs) and other targeted prodrug constructs.
• Bioconjugation & Probe Development: Used to create labeled peptides or protein conjugates for diagnostic assays and cellular imaging studies.
• Chemical Biology Studies: Acts as a tool compound for investigating enzyme-substrate interactions, receptor binding, and signal transduction pathways.
• Preclinical Development: Employed in formulation studies, pharmacokinetic profiling, and efficacy testing of new drug candidates.

Basic Information

Product Name	L-Tyr-D-Ala-Gly-n-[(1S)-3-Methyl-1-[[(3-Nitro-2-Pyridinyl)Dithio]Methyl]Butyl]-L-Phe-Nh2
CAS No.	120866-07-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	3-Nitro-2-pyridyl disulfide derivative of L-Tyr-D-Ala-Gly-Phe-NH2; Peptide-Disulfide Conjugate; S-(3-Nitro-2-pyridyl) derivative; Targeted Peptide Linker; ADC Linker Intermediate; CAS 120866-07-1; Custom Synthetic Peptide
EINECS	Contact for details

Quality Control

Our L-Tyr-D-Ala-Gly-n-[(1S)-3-Methyl-1-[[(3-Nitro-2-Pyridinyl)Dithio]Methyl]Butyl]-L-Phe-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, controlled environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Assay	≥ 90.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.