Description

(Pro7)-Neurokinin B CAS NO 120814-48-4 is a synthetic peptide analog of the endogenous neurokinin B (NKB) neuropeptide, designed for research and development applications. This compound is a critical tool for investigating the role of the neurokinin B/tachykinin receptor 3 (NK3R) signaling pathway in physiological and pathological processes. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies focused on neuroscience, endocrinology, and metabolic disorders.

Application

• Neuroscience Research: Used as a selective agonist to study the NK3 receptor's function in central and peripheral nervous systems.
• Endocrine System Studies: Investigates the role of NKB in the regulation of gonadotropin-releasing hormone (GnRH) pulsatility and reproductive function.
• Pharmacological Profiling: Serves as a reference standard in high-throughput screening (HTS) assays for drug discovery targeting the NK3 receptor.
• Biochemical Tool: Employed in receptor binding studies, signal transduction experiments, and cellular response characterization.
• Metabolic Research: Explores potential links between NKB signaling and energy homeostasis or metabolic pathways.
• Veterinary Research: Applied in studies of reproductive biology and neuroendocrinology in animal models.

Basic Information

Product Name	(Pro7)-Neurokinin B
CAS No.	120814-48-4
Molecular Formula	C55H79N15O13S
Molecular Weight	1154.4 g/mol
Synonyms	Neurokinin B (4-10), Pro7-NKB; [Pro7]-Neurokinin B; Asp-Met-His-Asp-Phe-Phe-Pro-Gly-Leu-Met-NH2; Tachykinin 3 (4-10) (human, bovine, canine, mouse, rat); NKB (4-10); NK3 Receptor Agonist (Pro7); H-Asp-Met-His-Asp-Phe-Phe-Pro-Gly-Leu-Met-NH2
EINECS	Contact for details

Quality Control

Our (Pro7)-Neurokinin B is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for critical research. Each lot is subjected to comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided with every shipment to support your regulatory and documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.