Description

4-n-Boc-2-Methyl-Piperazine is a high-purity, protected piperazine derivative widely used as a critical building block in organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex pharmaceutical molecules, particularly active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, including kinase inhibitors and other biologically active molecules.
• API Development: Used in the research and production of Active Pharmaceutical Ingredients (APIs) requiring a protected piperazine scaffold.
• Agrochemical Synthesis: Serves as a building block for creating advanced crop protection agents and herbicides.
• Chemical Research: Employed in academic and industrial R&D for method development and the construction of complex chemical libraries.
• Peptidomimetics: Utilized in the design and synthesis of peptide analogs and mimetics for therapeutic applications.
• Ligand Synthesis: Acts as a precursor for catalysts and ligands used in asymmetric synthesis and metal-organic frameworks.

Basic Information

Product Name	4-n-Boc-2-Methyl-Piperazine
CAS No.	120737-59-9
Molecular Formula	C10H20N2O2
Molecular Weight	200.28 g/mol
Synonyms	1-Boc-2-Methylpiperazine; tert-Butyl 2-methylpiperazine-1-carboxylate; 2-Methyl-1-(tert-butoxycarbonyl)piperazine; 1-(tert-Butoxycarbonyl)-2-methylpiperazine; 2-Methylpiperazine-1-carboxylic acid tert-butyl ester; N-Boc-2-methylpiperazine; 4-Boc-2-methylpiperazine; 2-Methyl-1-N-Boc-piperazine
EINECS	Contact for details

Quality Control

Our 4-n-Boc-2-Methyl-Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to meet the stringent requirements of pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.