Description

Ceftazidime Hydrate CAS NO 120618-65-7 is a third-generation, broad-spectrum cephalosporin antibiotic. It is valued for its potent activity against a wide range of Gram-negative bacteria, including Pseudomonas aeruginosa. This product is essential for the synthesis of active pharmaceutical ingredients (APIs) in the pharmaceutical industry. It serves as a critical intermediate for manufacturers producing sterile injectable antibiotics for hospital use.

Application

• Pharmaceutical API Synthesis: Primary raw material for the manufacture of Ceftazidime for Injection, a vital antibiotic.
• Antibiotic Formulations: Used in the production of finished dosage forms, particularly for treating serious infections like pneumonia, sepsis, and meningitis.
• Hospital & Critical Care Medicine: A key component in drugs used for empiric therapy in immunocompromised patients and those with hospital-acquired infections.
• Research & Development: Serves as a reference standard and starting material in antimicrobial research and new drug development projects.
• Veterinary Pharmaceuticals: Employed in the development of antibiotic treatments for bacterial infections in animals.

Basic Information

Product Name	Ceftazidime Hydrate
CAS No.	120618-65-7
Molecular Formula	C22H22N6O7S2 • xH2O
Molecular Weight	546.58 (Anhydrous basis)
Synonyms	Ceftazidime; Ceftazidime Pentahydrate; GR-20263; Tazicef; Fortaz; Ceptaz; Spectrum; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Glazidim
EINECS	Contact for details

Quality Control

Our Ceftazidime Hydrate is produced under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical manufacturing. We provide comprehensive Certificates of Analysis (COA) that include data for identification, assay, impurity profile, and residual solvents, referencing pharmacopeial methodologies. Compliance with cGMP guidelines and relevant ICH stability protocols is maintained throughout production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	10.0% - 13.0%
pH (1% Solution)	3.0 - 4.5
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.