Description

Dimethyl (3,3-Dimethyl-1-Butynyl)-Phosphonite is a specialized organophosphorus compound, CAS NO 120451-31-2, valued as a key intermediate in advanced organic synthesis. Its primary commercial significance lies in its role as a versatile building block for constructing complex molecular architectures, particularly in the development of pharmaceuticals and agrochemicals. This product is essential for research chemists and process development scientists in fine chemical, pharmaceutical, and agrochemical industries seeking to introduce phosphonite functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing phosphorus-based functional groups.
• Agrochemical Synthesis: Used in the production of novel pesticides, herbicides, and plant growth regulators where the phosphonite moiety is integral to biological activity.
• Ligand Precursor: Serves as a starting material for the preparation of specialized phosphonite ligands used in homogeneous catalysis, such as cross-coupling reactions.
• Material Science Research: Employed in the development of novel polymers and functional materials with tailored properties.
• Organic Synthesis Building Block: Facilitates the introduction of the (3,3-Dimethyl-1-Butynyl) group into complex molecules via phosphorus chemistry.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for high-value chemical products in pilot plants and manufacturing facilities.

Basic Information

Product Name	Dimethyl (3,3-Dimethyl-1-Butynyl)-Phosphonite
CAS No.	120451-31-2
Molecular Formula	C8H15O2P
Molecular Weight	174.18 g/mol
Synonyms	Dimethyl (3,3-Dimethylbut-1-yn-1-yl)phosphonite; (3,3-Dimethyl-1-butynyl)phosphonic Acid Dimethyl Ester; Phosphonic Acid, P-(3,3-Dimethyl-1-butyn-1-yl)-, Dimethyl Ester; Dimethyl P-(3,3-Dimethyl-1-butynyl)phosphonite; t-Butylacetylene Phosphonite Dimethyl Ester; 3,3-Dimethyl-1-butynylphosphonic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our Dimethyl (3,3-Dimethyl-1-Butynyl)-Phosphonite is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, GC, and HPLC, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every lot. We are committed to meeting the stringent requirements of our global customers in research and cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C to maximize stability. Due to its hygroscopic and easily oxidized nature, containers must be kept sealed and handled under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.