Description

2-Amino-4-(p-Tolyl)-1H-Pyrrole-3-Carbonitrile is a heterocyclic organic compound featuring a pyrrole core substituted with an amino group, a p-tolyl group, and a nitrile functionality. This unique structure makes it a valuable and versatile chemical intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists for constructing complex molecular architectures. The compound's reactivity profile allows for its use in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Precursor: Serves as a monomer or functional unit in the research of advanced polymers, dyes, and organic electronic materials.
• Chemical Synthesis: Employed in academic and industrial laboratories for methodological studies, including cyclization reactions and the construction of fused heterocyclic systems.
• Ligand and Catalyst Development: The amino and nitrile groups can be modified to create novel ligands for metal complexes used in catalytic processes.

Basic Information

Product Name	2-Amino-4-(p-Tolyl)-1H-Pyrrole-3-Carbonitrile
CAS No.	120450-05-7
Molecular Formula	C12H11N3
Molecular Weight	197.24 g/mol
Synonyms	2-Amino-4-(4-methylphenyl)-1H-pyrrole-3-carbonitrile; 4-(p-Tolyl)-2-amino-1H-pyrrole-3-carbonitrile; 2-Amino-4-(4-tolyl)-1H-pyrrole-3-carbonitrile; 1H-Pyrrole-3-carbonitrile, 2-amino-4-(4-methylphenyl)-; 2-Amino-4-(p-methylphenyl)-1H-pyrrole-3-carbonitrile; 120450-05-7; 2-Amino-4-(4-tolyl)pyrrole-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-4-(p-Tolyl)-1H-Pyrrole-3-Carbonitrile is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and physical characteristics. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.