Description

n-(2-Amino-2-Oxoethyl)-n-[(2S)-2-(3,5-Dioxo-1-Piperazinyl)Propyl]-Glycine is a specialized, high-purity chemical building block with significant value in advanced pharmaceutical synthesis. This compound matters for its role as a key intermediate in the development of complex active pharmaceutical ingredients (APIs), particularly those requiring specific stereochemistry and functional groups. Pharmaceutical R&D teams and fine chemical manufacturers need this material for producing sophisticated therapeutic agents, including protease inhibitors and other targeted biologics.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Protease Inhibitor Synthesis: Used in the research and production of specific enzyme inhibitors for therapeutic applications.
• Peptidomimetic Development: Serves as a core component in creating peptide-like molecules with enhanced stability and bioavailability.
• Bioconjugation Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems.
• Chemical Biology Research: Employed as a tool compound in studying enzyme-substrate interactions and signal transduction pathways.
• Fine Chemical Manufacturing: A key raw material for contract research and manufacturing organizations (CROs/CMOs) specializing in complex organic molecules.

Basic Information

Product Name	n-(2-Amino-2-Oxoethyl)-n-[(2S)-2-(3,5-Dioxo-1-Piperazinyl)Propyl]-Glycine
CAS No.	120418-76-0
Molecular Formula	C11H18N4O6
Molecular Weight	302.28 g/mol
Synonyms	N-(2-Amino-2-oxoethyl)-N-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]glycine; Glycine, N-(2-amino-2-oxoethyl)-N-[(2S)-2-(3,5-dioxo-1-piperazinyl)propyl]-; (2S)-1-[1-(Carboxymethylamino)-2-oxo-2-(2-aminoethylamino)ethyl]piperazine-2,6-dione; 120418-76-0; UNII-8V4A4N6W5I; 8V4A4N6W5I; SCHEMBL218024; AOB34017
EINECS	Contact for details

Quality Control

Our n-(2-Amino-2-Oxoethyl)-n-[(2S)-2-(3,5-Dioxo-1-Piperazinyl)Propyl]-Glycine is manufactured under strict quality systems suitable for pharmaceutical development. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure compliance with stringent industry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (S-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.5%; Any single unknown impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.