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Thrombospondin-Related Adhesive Protein, Protozoan CAS NO 120300-02-9
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CAS No.:120300-02-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Thrombospondin-Related Adhesive Protein, Protozoan is a specialized recombinant protein derived from protozoan sources, playing a critical role in cellular adhesion and host-pathogen interactions. This protein is essential for research and development in parasitology and vaccine development, offering a key tool for understanding infection mechanisms. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies focused on developing novel therapeutic and prophylactic interventions against protozoan diseases.
Application
- Parasitology Research: Fundamental studies on the adhesion and invasion mechanisms of protozoan parasites like Plasmodium and Toxoplasma.
- Vaccine Antigen Development: Serves as a target antigen in the research and pre-clinical development of vaccines against malaria and other parasitic infections.
- Diagnostic Reagent Production: Used in the development and calibration of immunoassays (ELISA, Western Blot) for detecting parasitic infections.
- Host-Pathogen Interaction Studies: Investigation of protein-protein interactions between parasite surface proteins and host cell receptors.
- Drug Discovery Screening: Target protein in high-throughput screening assays to identify potential inhibitors of parasitic adhesion and infection.
- Biomaterial and Biosensor Functionalization: Potential use in coating surfaces for studying specific cellular binding events in controlled environments.
Basic Information
| Product Name | Thrombospondin-Related Adhesive Protein, Protozoan |
| CAS No. | 120300-02-9 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | TRAP (Thrombospondin-Related Anonymous Protein); Circumsporozoite Protein and TRAP-related protein (CTRP); Plasmodium falciparum sporozoite surface protein; Sporozoite microneme protein essential for cell traversal; PfSPECT2; Pfs16; Malaria TRAP antigen; Protozoan adhesion protein. |
| EINECS | Contact for details |
Quality Control
Our recombinant protein products are manufactured under stringent quality systems. Each batch undergoes comprehensive analytical testing, including SDS-PAGE for purity assessment, Western Blot for immunoreactivity confirmation, and endotoxin level analysis to ensure suitability for cell-based applications. Certificates of Analysis (COA) detailing purity, concentration, and biological activity are provided with every shipment to guarantee consistent performance and research reproducibility.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted protein aliquots should be stored at -70°C to -80°C and avoid repeated freeze-thaw cycles. Due to its hygroscopic (moisture-sensitive) nature, protect the lyophilized powder from exposure to humid environments during handling.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (Western Blot) | Positive reaction with specific antisera |
| Purity (SDS-PAGE) | ≥ 90% |
| Protein Content (BCA) | ≥ 95% of stated weight |
| Endotoxin Level (LAL) | < 1.0 EU/µg |
| Biological Activity | Contact for details |
| Solubility | Soluble in appropriate aqueous buffers |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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